Fiscal Year 2009 Awards
Projects Conditionally Approved
Award Type |
Title |
Principal Investigator |
Collaborators |
Institutions |
Science Program |
Large, 2-year |
Expansile Nanoparticles for Tumor-Targeted Drug Delivery to Prevent Lymph Node Metastases in Breast Cancer | Yolonda Colson, MD, PhD | M. Grinstaff (BU) | BWH, BU | Biomaterials and Tissue Engineering |
Large, 2-year |
Droplet-based microfluidic chip for the cryopreservation of blood | Utkan Demirci, PhD | A. Khademhosseini (BWH), D. Kuritzkes (BWH) | BWH | Biodetection and Sepsis Control |
Large, 2-year |
Microfluidic blood Cleansing Device for Sepsis Therapy | Donald Ingber, MD, PhD | M. Puder (CHB), J. Wilson (CHB), J. Fiering (Draper), W. Yung (CHB) | CHB, Draper | Biodetection and Sepsis Control |
Large, 2-year |
A label-free viral detection microchip for point-of-care applications | Mehmet Toner, PhD | W. Rodriguez (MGH), S. Manalis (MIT), R. Sarpeshkar (MIT) | MGH, MIT | Biodetection and Sepsis Control |
Medium, 2-year |
Operating on the Heart from Within - A Minimally Invasive Approach to Treat Mitral Valve Disease | Robert A. Levine, MD | A. Slocum (MIT) | MGH, MIT | Cardiovascular Disease |
Medium |
Multi-Optode Probe for Evaluation of Diabetic Neuropathy | Peter Bergethon, PhD | S. Fanti (Tufts Univ) | BU, Tufts | Neurotechnology |
Medium |
Microelectrode Recordings and Advanced Algorithms for Seizure Prediction | Sydney Cash, MD, PhD | E. Brown (MGH), J. Guttag (MIT), W. Truccolo (MGH, Brown), L. Hochberg (MGH, BWH), E. Eskandar (MGH), J. Madsen (BWH, CHB) | MGH, MIT, Brown, BWH, CHB | Neurotechnology |
Medium |
Transcranial NIR Light for Traumatic Brain Injury | Michael Hamblin, PhD | M. Whalen (MGH), R. Anderson (MGH), P. D'Hemecourt (CHB) | MGH, CHB | Trauma and Casualty Care |
Medium |
Swimming capsule endoscope | Nobuhiko Hata, PhD | A. Tavakkolizadeh (BWH), G. Kosa (Swiss Federal Institute of Technology) | BWH, Swiss Federal Institute of Technology | Image Guided Therapy |
Medium |
Polymer Injection for Treatment of Ischemic Mitral Regurgitation | Judy Hung, MD, PhD | C. Morse (MGH), V. Wedeen (MGH), O. Muratoglu (MGH), R. Levine (MGH) | MGH | Cardiovascular Disease |
Medium |
A Microfluidic System for Monitoring Sepsis at the Point of Care | Catherine Klapperich, PhD | Y. Colson (BWH) | BU, BWH | Biodetection and Sepsis Control |
Medium |
Label-free detection and quantification of circulating leukocytes by in vivo flow cytometry | Charles Lin, PhD | A. Carlson (MGH), J. Gray (BIDMC), D. Hoganson (MGH) | MGH, BIDMC | Optical Diagnostics |
Medium |
Magnetic Endotracheal Tube Imaging Device | Rob Sheridan, MD | H. Ma (MIT), A. Slocum (MIT) | MGH, MIT | New Initiatives |
Medium |
Integrated OFDI-Fluorescence Catheter for Imaging of Atherosclerosis | Guillermo Tearney, MD, PhD | F. Jaffer (MGH) | MGH | Cardiovascular Disease |
Medium |
Antioxidant and Injectable Biodegradable Polymers to Promote Functional Recovery from Traumatic Spinal Cord Injury (SCI) | YD Teng, MD, PhD | R. Langer (MIT) | BWH, MIT | Trauma and Casualty Care |
Medium |
Novel ocular biomechanical analysis | Seok Yun, PhD | A. Grodzinsky (MIT), R. Pineda(MEEI) | MGH, MIT, MEEI | Optical Diagnostics |
Small |
Ultrasound-directed delivery of cancer chemotherapeutic drugs | Gerald Denis, PhD | T. Porter (BU), A. Cossi (BUMC) | BU, BUMC | Image Guided Therapy |
Small |
Computer-assisted tumor blood vessel tortuosity analysis at 3T, as a method of assessing ablative therapy response | Fiona Fennessy, PhD | E. Bullit (UNC), N. McDannold (BWH), C. Tempany (BWH) | BWH, UNC | Image Guided Therapy |
Small |
The effect of transcranial direct current stimulation combined with arm training using glove-ArMEO robotic device on motor recovery in traumatic brain injury survivors | Felipe Fregni, MD, PhD | P. Bonato (Spaulding) | BIDMC, Spaulding | Image Guided Therapy |
Small |
A Rapid Disposable Device for Early Detection of Sepsis | David Kaplan, PhD | J. Borenstein (Draper), S. Schachter (BIDMC) | Tufts, Draper, BIDMC | Biomaterials and Tissue Engineering |
Small |
Augmented reality glasses for the treatment of visuospatial neglect | Chun Lim, MD, PhD | D. Kaiser (Draper); E. Bergmann (Draper) | BIDMC, Draper | Neurotechnology |
Small |
Non-invasive measurement of intraepidermal nerve density | Dieter Manstein, MD | A. Oaklander (MGH) | MGH | Optical Diagnostics |
Small |
Near-infrared photobiostimulation as a means of neuromodulation in stroke | Alvaro Pascual-Leone, MD, PhD | A. Rotenberg (CHB) | BIDMC, CHB | Neurotechnology |
Small |
Development of safe and effective novel transtympanic membrane strategy for treatment of acute bacterial otitis media | Stephen Pelton, MD | D. Kohane (CHB/MIT), V. Sabharwal (BUMC) | BMC, BUMC, CHB, MIT | New Initiatives |
Small |
TDCS - Stroke Recovery | Gottfried Schlaug, MD, PhD | D. Alsop (BIDMC), C. Collins (Penn State) | BIDMC, Penn State | Neurotechnology |
Small |
Poly(glycerol sebacatge) film as barrier to formation of viscero-parietal peritoneal adhesions | Cathryn Sundback, ScD | P. Masiakos (MGH) | MGH | Biomaterials and Tissue Engineering |
CSI |
Healthcare 360: A technology-enabled model for general medical care | Ronald Dixon, MD | N. Sims (MGH) | MGH | Clinical Systems Innovation |
CSI |
Handwashing Compliance Reminder and Documentation | Ronald Newbower, PhD | B. Blakeney (MGH), A. Digiovine (MGH) | MGH | Clinical Systems Innovation |