Fiscal Year 1999 Awards

ENABLING TECHNOLOGIES

MINIMALLY-INVASIVE SURGERY
Endothelial activation markers - Cardiovascular Disease (CVD)
Michael Gimbrone, MD, BWH

Robot-assisted coronary bypass surgery
David Torchiana, MD, MGH

Lung volume reduction
Edward Ingenito, MD, PhD, BWH

3-D image-guided planning: endoscopically placed distraction device
Leonard Kaban, DDM, MD, MGH

OR of the future
David Rattner, MD, MGH

Indocyanine green for subsurface vessels
David Rattner, MD, MGH

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IMAGE-GUIDED TECHNOLOGY
Focused ultrasound-Tx breast cancer
Ferenc Jolesz, MD, BWH

Endoscopic imaging of fluorescence in the esophagus - ALA detection of dysplasia
Norman Nishioka, MD, MGH

Endoscopic optical coherence tomography-OCT
Norman Nishioka, MD, MGH

Segmentation of bone from CT & vessels from MRA
Carl-Fredrik Westin, PhD, BWH

Real-time registration of intra-op ultrasound with pre-op CT/MR for image guided therapy Eric Grimson, PhD, MIT

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BIOMATERIALS/TISSUE REPAIR
Poly nanoparticles: local high energy gene transfer
Robert Langer, ScD, MIT

Engineering vascularized tissue in-vitro for implant
Joseph Vacanti, MD, MGH

Engineering vascularized tissue in vitro for implant
Joseph Vacanti, MD, MGH and Jeffrey Borenstein, PhD, Draper

Develop tissue scaffold - intra articular use
Martha Meany-Murray, MD, MGH

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MEDICAL SIMULATION
Medical Simulation
Steven Dawson, MD, MGH and Mukund Desai, PhD, MIT

Enabling technology for medical simulation
Steven Dawson, MD, MGH and Kenneth Salisbury, PhD, MIT

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TRAUMA/CRITICAL CARE
Real-time blood assay
Brian Cunningham, PhD, Draper and Christopher Dubé, PhD, Draper

Multi RF diagnostic tool: trauma casualty care mgt
Geoffrey, S. Ling, MD, PhD, USUHS

NIR of tissue pH & O2 in ischemia
Juan Carlos Puyana, MD, MGH

Internet system: home-based health monitoring
William Wiesmann, MD, Harvey Mudd College

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VULNERABLE PLAQUE
Detection of vulnerable plaques: OCT
Brett Bouma, PhD, MGH

Preventing embolic brain injury
Joren Madsen, MD, MGH

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STROKE
Measure CV reactivity - functional MRI
Steven Greenberg, MD, MGH

Use of proton beam radiation for intractable epilepsy
Jonathan Brisman, MD, MGH

Laser thrombolysis of clot
Gonzalez, R. Gilberto, MD, PhD

Tissue characteristics in human acute ischemic stroke
Albert Lee, MD, MGH

Continuous monitoring stroke: diffuse optical tomography
David Boas, PhD, MGH

Assessment of neuroprotection
Gregory Sorensen, MD, MGH

NEW INITIATIVES

Improved tactile sensation for management of sensory deficits with stroke
Casey Kerrigan, MD, SRH

Transdermal drug delivery - skin electrophoresis
James Weaver, PhD, MIT