High-Risk Plaques: Detection and Management

 

May 3-4, 2008

The Colonnade Hotel

Boston, MA

 

 

Course Directors:

Thomas J. Brady, MD, Massachusetts General Hospital and CIMIT
Ahmed A. Tawakol, MD, Massachusetts General Hospital and CIMIT

Offered by:

Center for Integration of Medicine and Innovative Technology (CIMIT)
Harvard Medical School
Massachusetts General Hospital Departments of Medicine and Radiology

 

OBJECTIVE

This course will cover evolving concepts and novel methods for the identification of and therapy for patients at highest risk for developing myocardial infarction and stroke. Traditional diagnostic methods have proven invaluable for the management of atherosclerotic disease. Despite this, atherosclerosis remains the leading killer of Americans. A major reason for this may lie in our limited ability to identify patients at highest risk for developing myocardial infarction and stroke. An enhanced understanding of methods and therapies to detect and treat such vulnerable patients will be offered through this course.

 

Course Highlights

A dynamic and expert faculty will present state-of-the-art information and its application to clinical issues. Each session will be followed by a question and answer period and an extensive syllabus will be provided allowing you to review the material at home.

 

 

Program Schedule

 

Saturday, May 3

7:00 - 8:00 AM

Registration

 

8:00

Welcome

Ahmed Tawakol, MD

8:15-11:30

Session 1: Pathophysiology of Atherosclerosis

8:15 – 8:45

Defining the Vulnerable Plaque: New Pathologic Insights

Renu Virmani, MD, FACC

8:45 – 9:30

Inflammation and the Pathogenesis of Atherosclerosis

Peter Libby, MD

9:30-10:00

Break

 

10:00 – 10:30

Inflammatory Triggers of Plaque Rupture

Mohammad Madjid, MD

10:30 – 11:00

Mechanisms of the Acute Coronary Syndromes

Peter Libby, MD

11:00 – 11:30

Discussion

 

11:30 AM to 12:30PM

Lunch

 

12:30 to 5:20 PM

Session 2: Non-Invasive Detection Modalities

12:30 – 1:00

Biomarkers Overview

Paul Ridker, MD

1:00 – 1:30

What has Framingham Taught Us?

TBD

1:30 – 2:00

Lipids

Ernst Schaefer, MD

2:00 – 2:30

Discussion

 

2:30-2:45

Break

 

2:45 – 3:10

Imaging Biomarker Overview

Udo Hoffmann, MD

3:10 – 3:35

Carotid Ultrasonography 

Marie Denise Gerhard-Herman, MD

3:35 – 4:00

CT

Thomas Brady, MD

4:00 – 4:25

Positron Emission Tomography 

Ahmed Tawakol, MD

4:25 – 5:00

MRI

TBD

5:00-5:20

Discussion

 

5:20

Adjourn

 

5:20 – 6:00

Reception

 

 

 

Sunday, May 4

 

 

8:00 AM -12:15 PM

Session 3: Invasive Detection Modalities

8:00 – 8:30

Coronary Arteriography

Pallav Garg MBBS, FRACP, MSc 

8:30 – 9:00

IVUS and Virtual Histology

Ik-Kyung Jang, MD, PhD

9:00 – 9:30

Endothelial Shear Stress

Peter Stone, MD

9:30 –10:00

Discussion

 

10:00 –10:15

Break

 

10:15 – 10:45

Intravascular MRI and NIRF

Farouc Jaffer, MD, PhD

10:45 – 11:15

Near-Infrared  Spectroscopy

James Muller, MD

11:15 – 11:45

OCT

Gary Tearney, MD, PhD

11:45 –12:15

Discussion

 

12:15 –1:30

Lunch

 

1:30 – 4:00

Session 4: Management of High-Risk Plaques

1:30 – 2:00

Optimal Lipid Management

Jorge Plutzky, MD

2:00 – 2:30

Non-Lipid Pharmacotherapy

TBD

2:30 – 3:30

Should Drug-Eluting Stents Be Used to Treat VP?

 

 

Yes

Pallav Garg MBBS, FRACP, MSc 

 

No

Aloke Finn, MD

3:30-4:00

Discussion

 

4:00

Adjourn

 

                                               

               

2008 Faculty

 

Thomas J. Brady, MD

Co-Program Leader, Cardiovascular Disease; Director, Cardiovascular Imaging and Intervention; Director, Nuclear Medicine and Molecular Imaging and Vice Chairman, Director of Radiology Research, Massachusetts General Hospital; L.L Robbins Professor of Radiology, Harvard Medical School

 

Aloke Finn, MD
Assistant Professor of Medicine, Emory University School of Medicine

 

Pallav Garg MBBS, FRACP, MSc 
Division of Clinical Biometrics, Department of Cardiology, Brigham and Women's Hospital

 

Marie Denise Gerhard-Herman, MD
Medical Director, Vascular Diagnostic Laboratory, Brigham and Women’s Hospital

 

Udo Hoffmann, MD

Associate Professor of Radiology, Harvard Medical School; Director, Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital

 

 

Farouc Jaffer, MD, PhD

Assistant Professor of Medicine, Harvard Medical School; Director, Vascular Imaging, Cardiovascular Molecular Imaging Program; Attending Interventional Cardiologist, Cardiac Catheterization Laboratory, Massachusetts General Hospital

 

Ik-Kyung Jang, MD, PhD

Associate Professor of Medicine, Harvard Medical School; Director, Cardiology Laboratory for Integrated Physiology and Imaging, Massachusetts General Hospital

 

Peter Libby, MD

Mallinckrodt Professor of Medicine, Harvard Medical School, Chief of Cardiovascular Medicine, Brigham and Women’s Hospital

 

Mohammad Madjid, MD

Senior Research Scientist, Texas Heart Institute

 

James Muller, MD

Founder, CEO, President and Chief Medical Officer, InfraRedx

 

Jorge Plutzky, MD

Associate Professor of Medicine, Harvard Medical School; Director, The Vascular Disease Prevention Program, Brigham and Women’s Hospital

 

Paul Ridker, MD

Eugene Braunwald Professor of Medicine, Harvard Medical School; Director of the Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital

 

Ernst J. Schaefer, MD
Senior Scientist and Director, Lipid Metabolism Laboratory; Jean Mayer USDA HNRCA at Tufts University

 

Peter H. Stone, MD

Associate Professor of Medicine, Harvard Medical School; Co-Director, Cardiac Care Unit and Director, Clinical Trials Center, Brigham and Women’s Hospital

 

Ahmed A. Tawakol, MD
Co-Leader, CIMIT Cardiovascular Disease Program; Co-Director, Cardiac MR-PET-CT Program and Associate Director, Nuclear Cardiology, Massachusetts General Hospital

 

Guillermo Tearney, MD, PhD

Associate Professor of Pathology, Harvard Medical School; Wellman Center for Photomedicine, Massachusetts General Hospital; Program Leader, Optical Diagnostics, CIMIT

 

Renu Virmani, MD

President and Medical Director, CVPath, Institute, Inc.