Forum Abstract

A thorough evaluation of the gap between specific healthcare needs and available interventions provides direction for identifying opportunities to translate basic research findings into robust, clinically validated products for daily use. A decision to pursue the development of a new product includes many factors beyond the lab bench such as careful market research, a determination of the value that the intervention brings to the patient relative to alternatives, an assessment of the potential lifespan of the product, and how the product will perturb the current medical practice paradigm. Stool DNA analysis for detecting colorectal cancer and pre-cancer associated biomarkers moved from lab bench to inclusion in national screening guidelines over the course of a decade and is illustrative of this journey.

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