CIMIT's Listing of External Grants and Funding Opportunities

A current listing of external grants and government funding opportunities* identified as relevant to the CIMIT community. CIMIT and all affiliated entities do not endorse the information from external links, nor are they responsible for the availability, accuracy, or content of these sites.

Grants are listed in cronological order of application submission opening/due dates.
Grants marked New! are recent additions to the page.

* CIMIT and all affiliated entities do not endorse the information from external links, nor are they responsible for the availability, accuracy, or content of these sites.

New! DoD Air Force Office of Scientific Research Research Interests of the Air Force Office of Scientific Research (Modification 2)

Application Deadline: This is an open-ended BAA. Thus, this announcement will remain open until replaced by a successor BAA. Proposals may be submitted at any time.

Purpose: AFOSR plans, coordinates, and executes the Air Force Research Laboratory’s (AFRL) basic research program in response to technical guidance from AFRL and requirements of the Air Force; fosters, supports, and conducts research within Air Force, university, and industry laboratories; and ensures transition of research results to support USAF needs. The focus of AFOSR is on research areas that offer significant and comprehensive benefits to our national warfighting and peacekeeping capabilities. These areas are organized and managed in three scientific directorates: Aerospace, Chemical and Material Sciences (NA), Physics and Electronics (NE), and Mathematics, Information and Life Sciences (NL). The research activities managed within each directorate are summarized within this BAA. AFOSR solicits proposals for basic research through this general Broad Agency Announcement (BAA). This BAA outlines the Air Force Defense Research Sciences Program. AFOSR invites proposals for research in many broad areas. These areas are described in detail in Section I, Funding Opportunity Description. AFOSR is seeking unclassified, fundamental research white papers and proposals that do not contain proprietary information.

NIH. ARRA OS: Recovery Act 2009: Accelerating Adoption of Comparative Effectiveness Research Results by Providers and Patients (R18)

Purpose: This ASPE FOA, supported by funds provided to ASPE under the American Recovery and Reinvestment Act of 2009 (“Recovery Act” or “ARRA”), Public Law 111-5, invites grant applications from organizations that propose to develop and test interventions to improve the translation and adoption of existing comparative effectiveness research (CER) information and incorporate these findings into practice in both the public and private sectors. Doing so effectively would demonstrate a return on the CER investment, and, more importantly, improve the health of patients. Funds will be used to support organizations that 1) develop and implement evidence-informed and innovative CER-based adoption interventions targeting patients and/or providers; 2) develop proposals that test the implementation of CER-based adoption strategies within and across organizations and delivery systems and analyze any behavior change (in patients and/or providers) associated with the intervention. CER-based entails the applicant describing and justifying the existing comparative evidence that is the focus of the adoption intervention. Organizations applying for these funds will need to utilize existing or create new measurement systems to track adoption or adherence rates (thus measuring clinician and patient behavior changes) associated with the adoption of CER and measurement of health outcomes if possible. Applicants should also seek to understand the underlying factors associated with adoption.

Purpose: The Army and Navy, hereafter referred to as Department of Defense (DoD) Components, invite small business firms and research institutions to jointly submit proposals under this solicitation for the Small Business Technology Transfer (STTR) Program. The STTR Program is a program under which awards are made to small business concerns for cooperative research and development, conducted jointly by a small business and a research institution, through a uniform process having three phases. STTR, although modeled substantially on the Small Business Innovation Research (SBIR) Program, is a separate program and is separately financed. Subject to availability of funds, DoD Components will support high quality cooperative research and development proposals of innovative concepts to solve the listed defense-related scientific or engineering problems, especially those concepts that also have high potential for commercialization in the private sector.

The STTR Program is designed to provide a strong incentive for small companies and researchers at research institutions, i.e., non-profit research institutions, contractor-operated federally funded research and development centers (FFRDCs), and universities, to work together as a team to move ideas from the research institution to the marketplace, to foster high-tech economic development, and to address the technological needs of our armed forces. (See DoD's Critical Technology Areas).

Purpose: The NCRR Shared Instrument Grant (SIG) program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instrumentation or an integrated system that costs at least $100,000. The maximum award is $600,000. Types of instruments supported include confocal and electron microscopes, biomedical imagers, mass spectrometers, DNA sequencers, biosensors, cell sorters, X-ray diffraction systems, and NMR spectrometers among others.

NIH Recovery Act Limited Competition: Institutional Comparative Effectiveness Research Mentored Career Development Award (KM1)

Purpose: Through this Funding Opportunity Announcement (FOA), entitled “Institutional Comparative Effectiveness Research Mentored Career Development Award (KM1),” which is supported by funds provided to the NIH under the American Recovery & Reinvestment Act of 2009 (“Recovery Act” or “ARRA”), Public Law 111-5, the NIH invites applications from research-intensive institutions to support mentored career development in support of comparative effectiveness research (CER) in an interdisciplinary environment catering to the needs of diverse populations of scholars including (but not limited to) those with backgrounds in biostatistics, epidemiology, health economics, pharmacology, medicine, and dentistry. Scholars should be encouraged to register for higher degrees, where appropriate. Successful applicant institutions will be expected to include course development work in their proposal and make provision for expanding the pool of experienced CER mentors. This FOA is responsive to the NIH mission to build capacity in critical research areas http://www.nih.gov/about/index.html#mission.

Purpose: The Agency for Healthcare Research and Quality (AHRQ) is interested in funding a diverse set of projects that develop, test and evaluate various simulation approaches for the purpose of improving the safe delivery of health care. Simulation in health care predominately is a training technique that exposes individuals and teams to realistic clinical challenges through the use of mannequins, task trainers, virtual reality, or standardized patients, and allows participants to experience in real-time the consequences of their decisions and actions. The principal advantage of simulation is that it provides a safe environment for health care practitioners to acquire valuable experience without putting patients at risk. Simulation also can be used as a test-bed to improve clinical processes and to identify failure modes or other areas of concern in new procedures and technologies that might otherwise be unanticipated and serve as threats to patient safety. Applications that address a variety of clinical settings are sought.

Purpose: This funding opportunity announcement (FOA) solicits Research Demonstration (R18) Projects, and expresses AHRQ portfolio priority areas of interest for ongoing extramural health services research, demonstration, dissemination, and evaluation grants that propose to prevent and more effectively manage healthcare associated infections (HAIs).

PHS 2010-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])

Purpose: This Funding Opportunity Announcement (FOA) issued by the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA) and the Administration for Children and Families (ACF) invites eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) grant applications. United States SBCs that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH, CDC, FDA and ACF awarding components identified in this FOA are encouraged to submit SBIR grant applications in response to identified topics (see PHS 2010-2 SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, FDA and ACF.)

NIH Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (Parent F33)

Purpose: The National Institutes of Health (NIH) awards individual senior level research training fellowships to experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators in research fields relevant to the missions of participating NIH Institutes and Centers.

NIH NINDS Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows in MD-PhD programs (F31)

Purpose: The purpose of this individual predoctoral research training fellowship is to provide support for promising doctoral candidates who are enrolled in combined MD-PhD programs, who will be performing dissertation research and training in scientific health-related fields relevant to the mission of the National Institute of Neurological Disorders and Stroke.

CDMRP FY10 Prostate Cancer Research Program (PCRP) - Exploration - Hypothesis Development Award

Exploration - Hypothesis Development Award Pre-application Deadline: March 10, 2010

Purpose: Supports highly innovative, untested, potentially groundbreaking concepts in prostate cancer.

Purpose: Supports conceptually innovative, high-risk/high-reward research that could ultimately lead to critical discoveries or major advancements that will drive the field of ovarian cancer forward.

Purpose: Supports innovative translational research addressing a critical problem or question in ovarian cancer that will accelerate the movement of promising ideas toward clinical applications. Proposals are encouraged that specifically address critical needs of the ovarian cancer community in the following areas for the Translational Pilot Award only:

Initiation and precursor lesion of ovarian cancer
Novel approaches for the evaluation of predictive biomarkers
Understanding of the host and microenvironment
Novel imaging approaches for screening and management
Innovative insights into etiology and risk factors for ovarian cancer

CDMRP FY10 Peer Reviewed Medical Research Program (PRMRP) - Investigator-Initiated Research Award

Investigator-Initiated Research Award Pre-Application Submission Deadline: March 11, 2010

Purpose: Supports military-relevant health-related research that will make an original and important contribution to a field of research or patient care. Supports research that is responsive to the health care needs of the Armed Forces, their family members, and/or the U.S. veteran population. Must address an FY10 Topic Area. The FY10 PRMRP topic areas as provided by Congress are: Chronic Migraine and Post-traumatic Headache; Dystonia; Drug Abuse; Epilepsy; Fragile X Syndrome; Inflammatory Bowel Disease; Interstitial Cystitis; Listeria vaccine for infectious disease; Lupus; Mesothelioma; Neuroblastoma; Osteoporosis and related bone disease; Paget’s Disease; Pheochromocytoma; Polycystic Kidney Disease; Post-traumatic Osteoarthritis; Scleroderma; Social Work Research; Tinnitus.

CDMRP FY10 Bone Marrow Failure Research Program (BMFRP) - New Investigator Award

Purpose: Supports the career transition and/or continued development of promising, independent, non-mentored investigators, who are in the early stages of their scientific careers in the field of BMF disease research.

Purpose: This FOA encourages Research Conference Grant (R13) applications from institutions and organizations that propose to develop interdisciplinary research teams. Teams must include investigators from the social and/or behavioral sciences, and may include the life and/or physical sciences. The goal is to broaden the scope of investigation into scientific problems, yield fresh and possibly unexpected insights, and increase the sophistication of theoretical, methodological, and analytical approaches by integrating the analytical strengths of two or more disparate scientific disciplines while addressing gaps in terminology, approach, and methodology. This program will allow investigators from multiple disciplines to hold meetings in order to provide the foundation for developing interdisciplinary research projects.

Purpose: Supports high-impact studies toward reducing or eliminating the problem of overtreatment of primary prostate cancer. Areas of interest include but are not limited to active surveillance, biomarkers, improved staging and grading (including imaging), optimal measures for decision making pre- and post biopsy, optimal measures for follow-up and assessment of progression, and cancer care outcomes research (e.g., quality of life, survivorship) and surveillance.

ARHQ: ARRA OS Recovery Act 2009 Limited Competition: Comparative Effectiveness Delivery System Evaluation Grants (R01)

Purpose: This AHRQ Funding Opportunity Announcement (FOA), supported by funds provided to AHRQ under the American Recovery and Reinvestment Act of 2009 (Recovery Act or ARRA), Public Law 111-5, invites Research Project Grant (R01) applications from investigators seeking to conduct rigorous comparative evaluations of alternative system designs, change strategies, and interventions that have already been implemented in healthcare and are likely to improve quality and other outcomes.

Purpose: Supports three innovative investigators and their research teams in a coordinated and integrated translational research effort to address a question of major importance in breast cancer.

Transformative Vision Award Pre-Application Submission Deadline: March 18, 2010

Purpose: Supports research programs that have an extraordinary vision for dramatically transforming the prevention or treatment of breast cancer and a plan to test and implement the vision as quickly as possible. Focuses on achieving a visionary solution to a problem or question of overarching importance to breast cancer through an investigator-defined approach.

CDMRP FY10 Breast Cancer Research Program (BCRP) - Inter-Institutional Training Award

Inter-Institutional Training Award Pre-Application Submission Deadline: March 18, 2010

Purpose: Supports two or more faculty-level investigators at an organization that does not currently have a breast cancer research program to acquire mentored training in breast cancer research. Supports the establishment of a sustainable breast cancer research program at the applicant organization. Proposed research and training should lead to publication(s) and independent breast cancer research funding.

CDC Health Promotion and Disease Prevention Research Centers: Special Interest Project Competitive Supplements (SIPS) (U48)

Purpose: The purpose of the Prevention Research Centers (PRC) program’s Special Interest Projects (SIPS) is to support supplemental projects in health promotion and disease prevention research that: (1) focus on the major causes of death and disability, with an emphasis on underserved and minority populations (2) improve public health practice through community-based participatory research, and (3) designs, tests, disseminates, or translates effective public health programs at the state and community level. One of the major focuses of this supplemental funding program is to design, test, and disseminate effective prevention research strategies.

CDMRP FY10 Breast Cancer Research Program (BCRP) - Predoctoral Traineeship Award

Predoctoral Traineeship Award Pre-Application Submission Deadline: March 24, 2010

Purpose: Supports the training of promising graduate students studying breast cancer research under the guidance of a designated mentor. The predoctoral trainee is considered the PI and should write the proposal with appropriate direction from the mentor. Training program and mentorship should facilitate development of the PI as a breast cancer researcher.

CDMRP FY10 Breast Cancer Research Program (BCRP) - Postdoctoral Fellowship Award

Postdoctoral Fellowship Award Pre-Application Submission Deadline: March 24, 2010

Purpose: Supports the training of exceptionally talented recent doctoral graduates. Proposed research should be innovative and have the potential for high impact. Multidisciplinary training encouraged. Training program and mentorship should prepare the PI for an independent career at the forefront of breast cancer research.

New! CDMRP FY10 Breast Cancer Research Program (BCRP) - Era of Hope Scholar Award

Era of Hope Scholar Award Pre-Application Submission Deadline: March 24, 2010

Purpose: Supports exceptionally talented, creative early-career scientists who have demonstrated that they are the “best and brightest” in their fields

Purpose: Supports visionary individuals who have demonstrated creativity, innovative work, and leadership in any field. Provides opportunity to pursue novel, visionary, high-risk ideas that could ultimately lead to the eradication of breast cancer.

Purpose: Supports the exploration of a highly innovative new concept or untested theory. Must address an FY10 Topic Area. The FY10 PRMRP topic areas as provided by Congress are: Chronic Migraine and Post-traumatic Headache; Dystonia; Drug Abuse; Epilepsy; Fragile X Syndrome; Inflammatory Bowel Disease; Interstitial Cystitis; Listeria vaccine for infectious disease; Lupus; Mesothelioma; Neuroblastoma; Osteoporosis and related bone disease; Paget’s Disease; Pheochromocytoma; Polycystic Kidney Disease; Post-traumatic Osteoarthritis; Scleroderma; Social Work Research; Tinnitus.

CDMRP FY10 Bone Marrow Failure Research Program (BMFRP) - Exploration–Hypothesis Development Award

Exploration–Hypothesis Development Award Pre-Application Submission Deadline: March 25, 2010

Purpose: Supports initial exploration of innovative, untested, high-risk, potentially high-gain, and possibly groundbreaking concept.

Purpose: Supports conceptually innovative, high-risk/potentially high-reward research that could ultimately lead to critical discoveries toward understanding the causes and progression of MS and/or improvements in patient care and/or quality of life.

Purpose: Supports the exploration of a highly innovative new concept or untested theory that addresses an important problem relevant to MS.

New! NIH Advancing Regulatory Science through Novel Research and Science-Based Technologies (U01)

Purpose: This FOA, issued by the National Institutes of Health, encourages applications from institutions/organizations that propose to study the applicability of novel technologies and approaches towards the development and regulatory review of medical products (including drugs, biologics, and devices). This regulatory science initiative will foster the development, evaluation and availability of new or improved tools, methods, standards, and applied science that support a better understanding and improved evaluation of product safety, quality, effectiveness, and manufacturing throughout the product life cycle. This area of science has knowledge gaps that deserve special emphasis and would benefit from strategic coordination and planning by NIH and FDA. Advances in this area depend on the incorporation of cutting-edge science and evidence-based knowledge into regulatory decision making. Support through this FOA for regulatory science research will facilitate the translation of biomedical discoveries to improve prevention, treatment, and diagnosis of human health problems.

New! USAID Agency for International Development Child Survival Health Grants Program

Purpose: The Fiscal Year (FY) 2010 Request for Applications (RFA) for the Child Survival and Health Grants Program (CSHGP) focuses on innovation and operations research (OR) in delivery strategies for high impact maternal, newborn, and child health (MNCH) interventions. In addition, the RFA is seeking to attract new partners to contribute to innovation and expand and improve the capacity of partners to contribute to the Stop Tuberculosis (TB) strategy interventions in targeted countries to meet global TB targets. The CSHGP’s focus on innovation continues to strengthen a major shift in the program and in the criteria for selecting grantees and is closely aligned with the GH Bureau’s mandate for innovation and technical leadership.

New! CDC Prevention of Suicidal Behavior through the Enhancement of Connectedness (U01)

Purpose: The National Center for Injury Prevention and Control of CDC within HHS is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010" and to measuring program performance as stipulated by the Government Performance and Review Act (GPRA). This RFA addresses the “Healthy People 2010” priority area(s) of injury and violence prevention and is in alignment with National Center for Injury Prevention and Control performance goal(s) to conduct a targeted program of research to reduce injury-related death and disability. For more information, go to www.healthypeople.gov and http://www.whitehouse.gov/omb/mgmt-gpra/.

Purpose: This FOA issued by the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, solicits cooperative agreement grant applications from institutions/organizations that propose to develop a redesigned and enhanced Parkinson’s Disease Data Organizing Center. NINDS and NIEHS are committed to facilitating the collection and sharing of data related to clinical and translational research in Parkinson’s disease. The goal of this program is a resource that will serve the Parkinson’s disease (PD) research community by developing an ongoing repository for data from clinical trials and clinical studies, including epidemiologic and genetic studies, related to PD, and sharing of these data to enhance research. These data may include clinical as well as associated imaging, genetic, and neuropathology data elements. In addition, the Center will link clinical data with associated genetic, biospecimen, imaging, and neuropathology data as available in other databases. The Parkinson’s Disease Data Organizing Center also will develop a flexible web-based data entry system using standardized common data elements for PD clinical research studies that can be modified by investigators for a variety of clinical research studies. The center will also maintain an up-to-date listing of resources for researchers in the scientific community. Ongoing outreach efforts should be undertaken to maximize data sharing via this resource in order to optimize research in PD. The information technology employed should serve to optimize the accessibility and usefulness of the information within the data organizing center.

Purpose: Supports clinical trials relevant to Autism Spectrum Disorders (ASD). Clinical trials focusing on the following areas are encouraged:

Pharmacological interventions addressing mechanisms identified in genetics studies
Complementary and alternative medicine
Psychosocial interventions for adolescents and adults

Purpose: Supports the development of innovative, high-impact ideas that advance the understanding of ASD and that lead to improved outcomes. Applications in the following areas are encouraged:

Purpose: Supports product-driven research aimed at developing tools for use by the ASD research or clinical communities.

CDMRP DoD Tuberous Sclerosis Complex Research Program (TSCRP) Clinical Research Award

Purpose: The mission of the TSCRP is to encourage innovative research aimed at understanding the pathogenesis of TSC, and to translate these findings to the care of individuals with TSC. Within this context, the TSCRP encourages applications to the FY10 program that address these vital program focus areas:

TSC-related cognitive and developmental studies.
Innovative studies historically underrepresented in TSC research to include:
- TSC management in adults
- Skin involvement
- Individualized prognosis
- Epigenetic factors (with prognosis and variability issue)
- Cardiac involvement (lesions that spontaneously resolve)
- Metabolic and nutritional effects

This award may be used to support either: Clinical/Translational Research or Clinical trials

New! NIH New Approaches to Arrhythmia Detection and Treatment (Small Business Technology Transfer STTR [R41/R42])

Purpose: This Funding Opportunity Announcement (FOA) encourages Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that propose to improve our ability to detect, prevent, and treat all forms of cardiac arrhythmias. This initiative encourages SBCs to develop improved diagnostic and therapeutic tools, products, or devices for cardiac arrhythmia monitoring, detection and treatment.

New! DoD Office of Naval Research FY11 Communications and Networking Discovery and Invention

Purpose: Communications technology that can provide seamless, robust, connectivity is at the foundation of the Sea Power 21 and FORCEnet Vision "... to have the right information, at the right place, at the right time ..." The performance of Command and Control (C2) systems and decision making at all levels of command depend critically on reliable, interoperable, survivable, secure and timely communications and networking, and the availability of high capacity multimedia (voice, data, imagery) communication networks is fundamental to nearly all Department of Navy (DoN) missions. The current evolution of naval war fighting from a platform-centric to a network-centric paradigm depends on successfully meeting the implied need for significantly enhanced communications and networking capabilities of C2, sensor and weapon systems. These systems are deployed on a variety of platforms and users, both manned and unmanned, operating under challenging battlefield conditions (lack of infrastructure, mobility, spectrum, interference, multipath, atmospherics, size/weight/power constraint, etc.) in different environments (space, terrestrial and undersea). Goal: The goal of the Communications and Networking Program within the Office of Naval Research (ONR) Code 312 is to support the FORCEnet vision by developing measurable advances in technology that can directly enable and enhance end-to-end connectivity and quality-of-service for mission-critical information exchange among such widely dispersed naval, joint and coalition forces...

Innovations in Biomedical Computational Science and Technology Initiative (SBIR [R43/R44])

Purpose: This funding opportunity announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose innovative research in biomedical informatics and computational biology to promote the progress of biomedical research. There exists an expanding need to speed the progress of biomedical research through the power of computing to manage and analyze data and to model biological processes. The NIH is interested in promoting research and developments in biomedical computational science and technology that will support rapid progress in areas of scientific opportunity in biomedical research. As defined here biomedical computing or biomedical information science and technology includes database design, graphical interfaces, querying approaches, data retrieval, data visualization and manipulation, data integration through the development of integrated analytical tools, and tools for electronic collaboration, as well as computational research including the development of structural, functional, integrative, and analytical computational models and simulations.

Innovations in Biomedical Computational Science and Technology Initiative (STTR [R41/R42])

Purpose: Purpose This funding opportunity announcement (FOA) solicits Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that propose innovative research in biomedical informatics and computational biology to promote the progress of biomedical research. There exists an expanding need to speed the progress of biomedical research through the power of computing to manage and analyze data and to model biological processes. The NIH is interested in promoting research and developments in biomedical computational science and technology that will support rapid progress in areas of scientific opportunity in biomedical research. As defined here biomedical computing or biomedical information science and technology includes database design, graphical interfaces, querying approaches, data retrieval, data visualization and manipulation, data integration through the development of integrated analytical tools, and tools for electronic collaboration, as well as computational research including the development of structural, functional, integrative, and analytical computational models and simulations.

Purpsoe: DARPA seeks to understand the failure mechanisms for in-vivo neural recording interfaces. This will involve thorough tissue assessment using current and potential materials and designs. Ultimately, DARPA desires to develop predictive models of failure, robust indicators of interface reliability, repeatable insertion methodologies, and high-throughput biological test techniques. See full DARPA-BAA-10-32.

New! AHRQ ARRA OS Recovery Act 2009 Limited Competition: Comparative Effectiveness Delivery System Demonstration Grants (R18)

Purpose: This AHRQ Funding Opportunity Announcement (FOA), supported by funds provided to AHRQ under the American Recovery & Reinvestment Act of 2009 (“Recovery Act” or “ARRA”), Public Law 111-5, invites Research Demonstration and Dissemination Grant (R18) applications from organizations to conduct demonstrations of (1) broad strategies and/or specific interventions for improving care by redesigning care delivery, or (2) strategies and interventions for improving care by redesigning payment. (For examples and definitions of terms, see “Objectives of this Funding Opportunity” and “Nature of this Funding Opportunity”.) The demonstrations will aim to achieve major improvements in care quality (including clinical outcomes and other dimensions), improve access to care, reduce disparities, or improve population-based measures of health outcomes. The demonstration will address issues related to HHS priorities, including those of Medicare and Medicaid.

Letters of Intent Receipt Date(s):
Applications not related to HIV/AIDS: April 14, 2010.
HIV/AIDS-related Applications: July 23, 2010

Purpose: This Funding Opportunity Announcement (FOA) encourages exploratory/developmental planning grant applications proposing the development of innovative, collaborative research and research training projects, between high income country (HIC) and low- to middle-income country (LMIC) scientists, on brain and other nervous system function and disorders throughout life, relevant to LMICs. The planning grants are expected to lead to full research programs which contribute to the long-term goals of building sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, prevention, and treatment strategies that are applicable worldwide.

Purpose: This Funding Opportunity Announcement (FOA) encourages grant applications proposing the development and conduct of innovative, collaborative research and research training projects, between High Income country (HIC) and low- to middle-income country (LMIC) scientists, on nervous system function and disorders throughout life, relevant to LMICs. The collaborative research programs are expected to contribute to the long-term goals of building sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, treatment and prevention strategies that are applicable worldwide.

Purpose: This Funding Opportunity Announcement (FOA) issued by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), invites research applications for projects that support preclinical development of lead candidate vaccines, therapeutics, adjuvants or diagnostics against NIAID Category A, B, or C priority agents.

New! DoD Air Force Office of Scientific Research Air Force Fiscal Year 2010 High Energy Laser Multidisciplinary Research Initiative (HEL MRI)

Purpose: The Air Force Office of Scientific Research (AFOSR) manages the basic research investment for the U.S. Air Force (USAF). As a part of the Air Force Research Laboratory (AFRL), AFOSR’s technical experts foster and fund research within the AFRL, universities, and industry laboratories to ensure the transition of research results to support USAF needs. Using a carefully balanced research portfolio, research managers seek to create revolutionary scientific breakthroughs enabling the Air Force and U.S. industry to produce world-class, militarily significant, and commercially valuable products. To accomplish this task, AFOSR, in conjunction with the High Energy Laser - Joint Technology Office (HEL-JTO) is soliciting proposals for the Fiscal Year 2010 High Energy Laser Multidisciplinary Research Initiative (MRI). Proposals will be considered in the topics of novel components for high energy lasers, ultra-short, ultra-intense pulse lasers and laser effects, laser interactions, and materials, devices, and techniques for high average power solid-state lasers. The details of these topics are described in Section I, Funding Opportunity Description. See the Full Announcement. AFOSR is seeking unclassified, fundamental research proposals that do not contain proprietary information. Additionally, proposals should have a potential to transition to applied research at the end of the MRI performance period. It is anticipated that the awards will be made in the form of grants. AFOSR reserves the right to select and fund for award all, some, or none of the proposals in response to this announcement.

Application Deadlines in 2010: April 20, June 21, August 20, October 20, December 20

Purpose: The Agency for Healthcare Research and Quality (AHRQ), announces its continued interest in supporting conferences through its Small Grant Program for Conference Support. AHRQ seeks to support conferences that help to further its mission to improve the quality, safety, efficiency, and effectiveness of health care for all Americans. The types of conferences eligible for support include: 1) Research development - conferences where issues or challenges in the practice and delivery of health care are defined and a research agenda or strategy for studying them is developed; 2) Research design and methodology - conferences where methodological and technical issues of major importance in the field of health services research are addressed or new designs and methodologies are developed; 3) Dissemination and implementation conferences - where research findings and evidence-based information and tools are summarized, communicated and used by organizations and individuals that have the capability to use the information to improve the outcomes, quality, access to, and cost and utilization of health care services; and/or, 4) Research training, infrastructure and career development -conferences where faculty, trainees and students are brought together with stakeholders to develop, share or disseminate research products, experiences, curricula, syllabi, training competencies.

Application Deadlines: Apr 21, 2010; August 5, 2010 First Thursday in August, Annually Thereafter; February 03, 2011 First Thursday in February, Annually Thereafter

Purpose: The primary goal of the Strategic Technologies for Cyberinfrastructure (STCI) Program is to support activities that lead to innovative cyberinfrastructure but are not currently funded by other programs or solicitations. Eligible projects include development, deployment, research, and education necessary to create cyberinfrastructure, or creation of cyberinfrastructure that will enable innovative science and education. Proposals submitted to STCI should demonstrate a significant potential to transform multiple areas of science and/or education that depend on the development and deployment of CI.

CDMRP DoD Tuberous Sclerosis Complex Research Program (TSCRP) Idea Development Award

Purpose: Encourage high impact, innovative research that will drive the field forward. The mission of the TSCRP is to encourage innovative research aimed at understanding the pathogenesis of TSC, and to translate these findings to the care of individuals with TSC. Within this context, the TSCRP encourages applications to the FY10 program that address these vital program focus areas:

TSC-related cognitive and developmental studies.
Innovative studies historically underrepresented in TSC research to include:
- TSC management in adults
- Skin involvement
- Individualized prognosis
- Epigenetic factors (with prognosis and variability issue)
- Cardiac involvement (lesions that spontaneously resolve)
- Metabolic and nutritional effects

Purpose: Supports conceptually innovative, high-risk/high-reward research from all areas of basic, translational, clinical, behavioral, and epidemiological research. Innovation is the most important review criterion.

CDMRP FY10 Peer Reviewed Medical Research Program (PRMRP) - Clinical Trial Award

Purpose: Supports rapid implementation of clinical trials of novel interventions. Supports research that is responsive to the health care needs of the Armed Forces, their family members, and/or the U.S. veteran population. Must address an FY10 Topic Area. The FY10 PRMRP topic areas as provided by Congress are: Chronic Migraine and Post-traumatic Headache; Dystonia; Drug Abuse; Epilepsy; Fragile X Syndrome; Inflammatory Bowel Disease; Interstitial Cystitis; Listeria vaccine for infectious disease; Lupus; Mesothelioma; Neuroblastoma; Osteoporosis and related bone disease; Paget’s Disease; Pheochromocytoma; Polycystic Kidney Disease; Post-traumatic Osteoarthritis; Scleroderma; Social Work Research; Tinnitus.

CDMRP FY10 Peer Reviewed Medical Research Program (PRMRP) - Technology/Therapeutic Development Award

Technology/Therapeutic Development Award Pre-Application Submission Deadline: April 22, 2010

Purpose: Product-oriented: Supports military-relevant health-related development of pharmacologic agents (drugs or biologicals), devices, and/or clinical guidance that has the potential to make a strong impact on patient care. Supports research that is responsive to the health care needs of the Armed Forces, their family members, and/or the U.S. veteran population. Must address an FY10 Topic Area. The FY10 PRMRP topic areas as provided by Congress are: Chronic Migraine and Post-traumatic Headache; Dystonia; Drug Abuse; Epilepsy; Fragile X Syndrome; Inflammatory Bowel Disease; Interstitial Cystitis; Listeria vaccine for infectious disease; Lupus; Mesothelioma; Neuroblastoma; Osteoporosis and related bone disease; Paget’s Disease; Pheochromocytoma; Polycystic Kidney Disease; Post-traumatic Osteoarthritis; Scleroderma; Social Work Research; Tinnitus.

DoD, Defense Advanced Research Projects Agency (DARPA) - Defense Sciences Office: Reorganization and Plasticity to Accelerate Injury Recovery (REPAIR) Grant

Purpose: DARPA seeks new methods for analysis and decoding of neural signals in order to understand how neural-based sensory stimulation could be applied to accelerate recovery from brain injury. Ultimately, it is desired to develop models of neural codes and temporal patterns that can provide an ability to interpret and predict changes in neural organization through plasticity at multiple scales of measurement.

New! SAMHSA Substance Abuse & Mental Health Services Adminis. Family Centered Substance Abuse Treatment Grants for Adolescents and their Families (Short Title: Assertive Adolescent and Family Treatment)

Purpose: The Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Treatment is accepting applications for fiscal year (FY) 2010 Family Centered Substance Abuse Treatment Grants for Adolescents and their Families (Assertive Adolescent and Family Treatment). The purpose of this program is to provide substance abuse services to adolescents and their families/primary caregivers in geographic areas with unmet need. Grantees will implement evidence-based practices, specifically the Adolescent Community Reinforcement Approach (A-CRA) coupled with Assertive Continuing Care (ACC), that are context specific focusing on the interaction between youth and their environments, family centered and community-based. Families/primary caregivers are an integral part of the treatment process and their inclusion increases the likelihood of successful treatment and reintegration of the adolescents into their communities following the period of formalized treatment.

New! NIH Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32)

Purpose: The Jointly Sponsored NIH Predoctoral Training Program in the Neurosciences supports broad and fundamental, early-stage graduate research training in the neurosciences via institutional NRSA research training grants (T32) at domestic institutions of higher education. Trainees are supported during years 1 and 2 of their graduate training when they are typically not committed to a dissertation laboratory. The primary objective is to prepare qualified individuals for careers in neuroscience that have a significant impact on the health-related research needs of the Nation.

Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to support dissemination and implementation studies to (1) develop innovative approaches to translating efficacious treatments and effective prevention modalities for heart, lung, and blood diseases and sleep disorders to the clinic, community, and/or other real-world settings; (2) test the effectiveness, sustainability, determinants, and cost-effectiveness of these approaches in real-world settings; and (3) examine the effectiveness of interventions as they are disseminated and implemented in real-world settings to reduce risk factors for and enhance prevention and treatment of heart, lung, and blood diseases and sleep disorders.

Purpose: The National Science Foundation (NSF), through the Directorate for Engineering's Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET), and the U.S. Food and Drug Administration (FDA), through its Center for Devices and Radiological Health (CDRH) have established the NSF/FDA Scholar-in-Residence Program at FDA. This program comprises an interagency partnership for the investigation of scientific and engineering issues concerning emerging trends in medical device technology. This partnership is designed to enable investigators in science, engineering, and mathematics to develop research collaborations within the intramural research environment at the FDA.

NIH/NCI Application and Early Stage Development of Emerging Technologies in
Cancer Research (R21)

Letters of Intent Receipt Date(s): April 27, 2010; August 30, 2010
Application Due Date(s): May 27, 2010; September 30, 2010

Purpose: This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), solicits grant applications that propose exploratory research projects on the initial application of emerging analytical technologies as laboratory or clinical tools. An “emerging technology” is defined as one that has passed the initial developmental stage, but has not yet been evaluated within the context of its intended use. Projects proposed in response to this FOA should have the potential to produce a major impact in a broad area of cancer-relevant research. If successful, these technologies would accelerate research in cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. This FOA solicits R21 applications that have high potential impact and allows for an element of technical risk; preliminary data are not required. All projects must include quantitative milestones (i.e. technical metrics that determine whether the specific aims have been accomplished). Projects proposing to use established technologies where the novelty resides in the biological or clinical question being pursued are not appropriate for this solicitation and will be returned as non-responsive. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

Letters of Intent Receipt Date(s): April 27, 2010; August 30, 2010
Application Due Date(s): May 27, 2010; September 30, 2010

Purpose: This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), solicits grant applications proposing technically innovative feasibility studies focused on early stage development of cancer-relevant technologies. If successful, these technologies would accelerate the research and understanding of basic cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. This FOA solicits R21 applications and is suitable for projects at their inception, conceptual or idea based, where technical feasibility of the proposed technology or methodology has not yet been established. The R21 mechanism requires high potential impact and allows for an element of technical risk; projects proposed in response to this FOA may reflect this level of risk but must have concurrent potential to produce a major impact in a broad area of cancer-relevant research. All projects must include quantitative milestones (i.e. technical metrics that determine whether the specific aims have been accomplished). Projects proposing to use technology that is already established or projects where the novelty resides in the biological or clinical question being pursued are examples of topics not appropriate for this solicitation and will be returned as non-responsive. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

NIH/NCI Validation and Advanced Development of Emerging Technologies
for Cancer Research (R33)

Letters of Intent Receipt Date(s): April 27, 2010; August 30, 2010
Application Due Date(s): May 27, 2010; September 30, 2010

Purpose: This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), solicits grant applications proposing research projects on the advanced development of emerging molecular and cellular analysis technologies through technical/analytical validation in an appropriate cancer-relevant biological system. An “emerging technology” is defined as one that has passed the pilot developmental stage and shows promise, but has not yet been evaluated within the context of its intended use. If successful, these technologies would accelerate research in cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. This FOA solicits R33 applications; this mechanism is suitable for projects where “proof-of-principle” of the proposed technology or methodology has been established and supportive preliminary data are available. Projects proposed to this FOA should reflect the potential to produce a major impact in a broad area of cancer-relevant research. Projects proposing to use established technologies where the novelty resides in the biological or clinical question being pursued are not appropriate for this solicitation and will be returned as non-responsive. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

New! CDMRP DoD Tuberous Sclerosis Complex Research Program (TSCRP) Career Transition Award

Purpose: Supports TSC researchers during the transition from postdoctoral training to an independent position.

New! CDMRP DoD Tuberous Sclerosis Complex Research Program (TSCRP) Exploration Hypothesis Development Award

Purpose: Funds the initial exploration of innovative, untested research and pursue serendipitous observations.

New! CDMRP DoD FY10 Neurofibromatosis Research Program (NFRP) Clinical Trial Award

Purpose: Fund Phase 0, I, or II clinical trials relevant to neurofibromatosis (NF) and/or Schwannomatosis. Combinations of phases are permitted.

New! CDMRP DoD FY10 Neurofibromatosis Research Program (NFRP) Investigator-Initiated Research Award

Purpose: Fund basic and clinically oriented research relevant to NF and/or Schwannomatosis.

New! CDMRP DoD FY10 Neurofibromatosis Research Program (NFRP) Investigator-Initiated Focused Research Award

Purpose: Fund basic and clinically oriented research relevant to NF and/or Schwannomatosis. Proposals must address one or more of the following research focus areas: Pain, wound repair, nerve regeneration, stress and inflammation, cognitive dysfunction and health-related quality of life, and/or neurofibromin protein.

Purpose: Fund the initial exploration of innovative, untested research and pursue serendipitous observations.

Purpose: Enable recent medical or other doctoral degree graduates to obtain the necessary experience to pursue an independent career in NF research.

New! SAMHSA Substance Abuse & Mental Health Services Adminis. Mental Health Transformation Grants

Purpose: The Substance Abuse and Mental Health Services Administration, Center for Mental Health Services is accepting applications for fiscal year (FY) 2010 Mental Health Transformation Grants (MHTG). The purpose of this program is to foster adoption and implementation of permanent transformative changes in how public mental health services are organized, managed and delivered so that they are consumer-driven, recovery-oriented and supported through evidence-based and best practices. Funding will support States and local governments to create and/or expand treatment capacity within SAMHSA’s strategic initiatives. SAMHSA’s Center for Mental Health Services (CMHS) was charged with responsibility to foster implementation of the recommendations laid out by the New Freedom Commission on Mental Health in their 2003 report Achieving the Promise: Transforming Mental Health Care in America...

Purpose: The purpose of this Funding Opportunity Announcement is to provide a vehicle for submitting grant applications for investigator-initiated multi-site Phase II or Phase III randomized, controlled clinical trials. The trials may address any research question related to the mission and goals of NHLBI and may test clinical or behavioral interventions. Investigators should consult the NHLBI’s Guidelines for Investigator Initiated Clinical Trials (http://www.nhlbi.nih.gov/funding/policies/clinical.htm) for more detailed instructions and information about multi-site clinical trial grant applications. Additional information about the mission, strategic plan and research interests of the NHLBI can be found at NHLBI’s website (http://www.nhlbi.nih.gov/index.htm).

New! NIH NIDCD Research on Accessible and Affordable Hearing Health Care (R24)

Purpose: The NIDCD is encouraging R24 Developmental Grant applications that will lead to research addressing accessible and affordable hearing health care (HHC) for adults with mild to moderate hearing loss. The intent of this FOA is to provide support for the creation of new partnerships among researchers and/or between researchers and interested organizations (e.g., academia, health care organizations, industry, and patient organizations) and for the conduct of developmental and planning activities for future research applications. The final objective of the R24 must be the submission of specific competitive research grant applications (i.e., R01s, R21s, R43/R44, P50s). The R24 is designed to support new collaborations and is not designed to support groups of investigators who would normally interact and collaborate in the absence of an R24.

Purpose: This funding opportunity announcement (FOA) issued by National Institute on Deafness and Other Communication Disorders (NIDCD) invites Exploratory/Developmental Phased Innovation (R21/R33) grant applications from organizations/institutions to support research and/or infrastructure needs leading to accessible and affordable hearing health care (HHC). Applications may request research and/or infrastructure support. This FOA seeks milestone-driven research applications exploring new or innovative adaptations of approaches designed to increase access and affordability of hearing health care. Applications should be focused on delivering better healthcare access and outcomes and should seek solutions that are effective, affordable and deliverable to those who need them. This FOA uses the R21/R33 grant mechanism and requires a separate statement that justifies the need for the mechanism and describes anticipated milestones.

New! NSF Small Business Innovation Research Program Phase I Solicitation FY-2011 (Release 1) (SBIR)

Purpose: The primary objective of the NSF SBIR Program is to increase the incentive and opportunity for small firms to undertake cutting-edge, high risk, high quality scientific, engineering, or science and engineering education research that would have a high potential economic payoff if the research is successful.

Purpose: This Funding Opportunity Announcement (FOA), issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), invites applications for Centers of Research Translation (CORT) (P50). It is expected that a CORT will have a disease-targeted translational theme with individual projects providing synergy for the theme, directed at elucidating the relevance of basic research to human disease in an area within the NIAMS mission. Two major features of the CORT program include: 1) the overarching aim of disease-specific research translation, and 2) the inclusion of resources and an administrative structure to facilitate research translation.

Purpose: This Funding Opportunity Announcement (FOA) issued by the National Heart, Lung, and Blood Institute and the National Cancer Institute, National Institutes of Health, solicits Research Project Grant (R01) applications from institutions/organizations to identify the fundamental etiopathogenetic commonalities between lung cancer and Chronic Obstructive Pulmonary Disease (COPD) in order to characterize: (a) the genotypic and phenotypic characteristics that determine individual susceptibility; and (b) the shared biochemical, molecular, and immunological pathways involved in the origin and progression of the two diseases.

New! NIH Collaborative Research on the Transition From Acute to Chronic Pain: New Models and Measures in Clinical and Preclinical Pain Research (R01)

Purpose: The overall goal of this FOA is to stimulate preclinical and clinical research that will accelerate our understanding of the biological and behavioral determinants driving the transition from acute pain to chronic pain disorders. An understanding of the mechanisms and risk factors that determine who will transition to a chronic pain state is necessary in order to intervene in this transition and to design new, effective treatments to resolve acute pain before it becomes chronic. The objectives of this FOA are to: 1) assemble research teams with expertise in basic and clinical pain research and related expertise outside the pain field that will provide novel, collaborative, multidisciplinary approaches to answer crucial questions about the transition from acute to chronic pain; 2) discover biological and behavioral mechanisms that drive the transition from an acute pain state to a chronic dysfunctional pain condition; 3) develop new clinical and preclinical models and measures of pain that will be essential to identify and characterize these mechanisms. Studies that involve considerable risk but with the potential for breakthroughs in the field are strongly encouraged.

New! NIH MARC Undergraduate Student Training in Academic Research (U-STAR) National Research Service Award (NRSA) Institutional Research Training Grant (T34)

Purpose: The National Institute of General Medical Sciences (NIGMS) will award Minority Access to Research Careers (MARC) Undergraduate Student Training in Academic Research (U-STAR) National Research Service Act (NRSA) Training grants to eligible institutions as a means of supporting undergraduate academic and research training to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nation’s biomedical and behavioral research agenda. The MARC U-STAR program is designed to have a significant impact on the health-related research needs of the Nation by providing support to students underrepresented in the biomedical and behavioral sciences and improving their preparation for highly selective Ph.D. level training and future careers. The program supports efforts to strengthen the science/math course curricula, pedagogical skills of faculty, and biomedical research training at institutions with significant enrollments of students from underrepresented groups.

New! NIH NIAMS Accelerating Research Translation (ART) in Musculoskeletal and Skin Tissue Engineering and Regenerative Medicine Competitve Revision Award (R01)

Purpose: The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) solicits Accelerating Research Translation (ART) applications in musculoskeletal and skin tissue engineering and regenerative medicine (TE/RM). The ART awards intend to offer revision support (formerly referred to as a “competing supplement”) to active NIAMS R01, P01 and P50 (parent) grants for conducting large animal pre-clinical studies with the potential to immediately lead to human trials in musculoskeletal and skin TE/RM. These studies will 1) provide data required for Phase I/II human clinical trials in musculoskeletal and skin TE/RM, 2) demonstrate efficacy of a TE/RM therapy in musculoskeletal and skin TE/RM, or 3) develop pre-clinical large animal models that will have the potential to immediately lead TE/RM research into Phase I/II clinical trials. Early stage translational studies using small animals such as rodent and rabbit are not responsive to this FOA.

New! NIH NIAMS Accelerating Research Translation (ART) in Musculoskeletal and Skin Tissue Engineering and Regenerative Medicine Competitive Revision Award (P01 and P50)

Purpose: The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) solicits Accelerating Research Translation (ART) applications in musculoskeletal and skin tissue engineering and regenerative medicine (TE/RM). The ART awards intend to offer revision support (formerly referred to as a “competing supplement”) to active NIAMS R01, P01 and P50 (parent) grants for conducting large animal pre-clinical studies with the potential to immediately lead to human trials in musculoskeletal and skin TE/RM. These studies will 1) provide data required for Phase I/II human clinical trials in musculoskeletal and skin TE/RM, 2) demonstrate efficacy of a TE/RM therapy in musculoskeletal and skin TE/RM, or 3) develop pre-clinical large animal models that will have the potential to immediately lead TE/RM research into Phase I/II clinical trials. Early stage translational studies using small animals such as rodent and rabbit are not responsive to this FOA.

Purpose: The Neural Systems Cluster focuses on how complex functions arise from communication among the cellular elements of the nervous system and from interactions with other physiological systems and the environment. The Cluster encourages a systems biology approach to understand how emergent neural properties such as robustness, adaptability and resilience arise in the context of environmental, genetic and evolutionary influences.

Investigations may range over time scales from the physiological to the evolutionary. Studies may range in complexity from molecular and cellular processes to the behaviors that emerge from these processes and the feedback that these behaviors exert on the system. The use of comparative and evolutionary studies, as well as the development of novel theoretical, computational, and transdisciplinary approaches to guide and instruct experimental design, are particularly encouraged.

Purpose: The Physiological and Structural Systems Cluster supports research aimed at furthering the understanding of organisms as integrated units of biological organization. The Cluster considers proposals focused on interacting physiological and structural systems, their environmental and evolutionary contexts, and how these components are constrained by their integration into the whole organism. Projects that use systems approaches to understand why particular patterns of architecture and regulatory control have emerged as general organismal properties are particularly encouraged. Understanding how and why emergent organismal properties such as robustness, adaptability and resilience arise in the context of environmental, genetic, biochemical and morphological variation are of interest. The Cluster encourages model building to augment traditional experimental approaches in order to guide research on complex functional networks. Multidisciplinary approaches to the study of organismal systems including research at the interfaces of biology, physics, chemistry, mathematics, computer science and engineering are encouraged in each of the following areas: Symbiosis, Defense and Self-recognition; Processes, Structures and Integrity; Organism-Environment Interactions.

Purpose: The National Heart, Lung, and Blood Institute (NHLBI) encourages grant applications under this Funding Opportunity Announcement (FOA) to develop and implement a Knowledge Base (KB) and Coordinating Center for the Consortium of Cross Organ Mechanism-Associated Phenotypes for Genetic Analyses of Heart, Lung, Blood, and Sleep Diseases (MAPGen for HLBS). This is one of two FOAs for the MAPGen program. The other FOA is for the Research Centers (RCs) of MAPGen and described separately in RFA-HL-11-005. The MAPGenKB will provide logistical and informatics support for the research across all RCs in the MAPGen consortium and synthesize the knowledge from the datasets of the RCs and other sources that are relevant to the goals of the MAPGen consortium. The data and tools generated from this consortium will be made available to the broad scientific community.

New! NIH Development of Outcome Measures to Determine Success of Hearing Health Care (R01)

Letters of Intent Receipt Date(s): September 1, 2010, May 1, 2011, January 1, 2012

Purpose: This FOA, issued by the National Institute on Deafness and Other Communication Disorders, National Institutes of Health, encourages Research Project Grant (R01) applications from institutions/organizations that propose to develop and evaluate a set of outcome measures to determine the success of hearing health care for adults with hearing loss. There is a compelling need to identify the variables contributing to successful hearing health care outcomes, particularly the patient-centered and instrument-centered variables contributing to successful hearing aid use.

Purpose: The Clinical and Translational Science Award (CTSA) initiative assists institutions to create an integrated academic home for Clinical and Translational Science that has the resources to train and advance multi- and inter-disciplinary investigators and research teams with access to innovative research tools and information technologies that apply new knowledge and techniques to patient care. Clinical and Translational Science Awards (CTSAs) attract basic, translational, and clinical investigators, community clinicians, clinical practices, networks, professional societies, and industry to develop new professional interactions, programs, and research projects. Through innovative advanced degree programs, CTSAs foster the discipline of Clinical and Translational Science that is broader and deeper than their separate components (definitions of Clinical and Translational Science are provided in Section I of this posting).

Application Submission Windows:
Letters of Intent Deadline(s): September 28, 2010; September 28, 2011
Application Deadline(s): October 28, 2010; October 28, 2011

Purpose: The program will fund the 5-year P50 ICMIC grants to support interdisciplinary scientific teams conducting cutting-edge cancer molecular imaging research. ICMIC funding is designed to: (1) support innovative cancer molecular imaging research projects; (2) support unique core facilities; (3) enable the awardees to initiate pilot research in new promising directions; and (4) provide interdisciplinary career development opportunities for investigators new to the field of molecular cancer imaging

Purpose: These grants are to provide a rapid funding mechanism for research on the post-impact of disasters, in order to permit access to a disaster area in the immediate aftermath of the event.

Purpose: The Agency for Healthcare Research and Quality (AHRQ), announces its continued interest in supporting conferences through its Large or Recurring Grant Program for Conference Support. AHRQ seeks to support conferences that help to further its mission to improve the quality, safety, efficiency, and effectiveness of health care for all Americans. The types of conferences eligible for support include: 1) Research development - conferences where issues or challenges in the practice and delivery of health care are defined and a research agenda or strategy for studying them is developed; 2) Research design and methodology - conferences where methodological and technical issues of major importance to the field of health services research are addressed or new designs and methodologies are developed; 3) Dissemination and implementation - conferences where research findings and evidence-based information and tools are summarized, communicated and used by organizations and individuals that have the capability to use the information to improve the outcomes, quality, access to, and cost and utilization of health care services; and/or, 4) Research training, infrastructure and career development -conferences where faculty, trainees and students are brought together with stakeholders to develop, share or disseminate research products, experiences, curricula, syllabi, or training competencies. AHRQ is especially interested in supporting conferences that include plans for disseminating complimentary conference materials and products beyond the participants attending the event. Such strategies might include, but are not limited to, submitting articles for publication, posting information on a Web site, and seeking formal opportunities to discuss conference information with others.

Purpose: The purpose of this Funding Opportunity (FOA) is to support Research Demonstration and Dissemination (R18) grant applications from organizations that will implement safe practice interventions that demonstrate evidence of reducing or eliminating medical errors, risks, hazards, and harms associated with the process of health care. These 24 month implementation projects will inform AHRQ, providers, patients, payers, policy makers, and the public about how safe practice interventions can be successfully implemented in diverse health care settings and lead to safer and better health care for all Americans. This FOA follows the release of an earlier FOA in 2005 that resulted in the release of successful implementation projects and toolkits available to the public. Background information on the earlier FOA can be found at http://grants1.nih.gov/grants/guide/FOA-files/FOA-HS-05-012.html. Examples of and Information on projects from the initial Partnerships in Implementing Patient Safety FOA can be found at http://www.ahrq.gov/qual/pips/.