PERFORMING SURGICAL PROCEDURES WITHOUT MAKING INCISIONS ON THE SURFACE OF THE BODY OR LEAVING SCARS
CIMIT’s Minimally Invasive Surgery progam is focused on making surgery safer and more precise, exploring the next generation of less invasive surgical therapy. Recent projects involve developing tools and procedures for Natural Orifice Translumenal Endoscopic Surgery (NOTES), which could make surgery completely free of incisions, while drastically reducing the chances of infection, pain, and disability. Through the NOTES initiative, many complex surgeries could eventually become outpatient procedures.
Using newly developed NOTES devices, no external incision is necessary as surgeons gain access to the surgical field through a natural orifices. The hypothesis is that by avoiding incisions in the abdominal wall, risks of infection, pain and disability will be minimized and recovery either shortened or eliminated. Many procedures could be so radically improved that patients might even be able to return to a normal routine immediately.
In 2008, CIMIT awarded its $2.1 million, three-year, CIMIT Strategic Project grant to a multi-disciplinary, multi-institutional team studying and advancing the surgical procedure NOTES. With this award, CIMIT’s investment in NOTES research will top $3 million overall, making CIMIT the largest financial sponsor of this technology worldwide.
Current Funded NOTES Projects
|YEAR||PRINCIPAL INVESTIGATOR||INSTITUTION||PROJECT TITLE|
|2010-2008||David Rattner, MD, and
Chris Thompson, MD, MSc
|Massachusetts General Hospital & Brigham and Women’s Hospital||Strategic Project on Natural Orifice Translumenal Endoscopic Surgery|
|2008||Marvin Ryou||Brigham and Women’s Hospital||Magnetic Retraction for Advanced NOTES Procedures|
|2008||Marvin Ryou||Brigham and Women’s Hospital||Systematic Mapping of NOTES Access Sites in Human Cadavers|
Contact Commercialization Opportunities.for more information regarding
Recent Publications by CIMIT Investigators
|Willingham, F. F., Gee, D.W., Lauwers, G., Brugge, W. R., Rattner, D. W.||Surg Endosc.
|Natural Orifice Transesophageal Mediastinoscopy and Thoracoscopy||2008|
|Alam, H. B., Shults, C., Ahuja, N., Ayuste, E. C., Chen, H., Koustova, E., Sailhamer, E. A., Li, Y., Liu, B., de Moya, M., Velmahos, G. C.||Resuscitation
Sep 4, 2007
|Impact of Resuscitation Strategies on the Acetylation Status of Cardiac Histones in a Swine Model of Hemorrhage||2007|
|Sailhamer, E. A., Chen, Z., Ahuja, N., Velmahos, G. C., de Moya, M., Rhee, P., Shults, C., Alam, H. B.||J Am Coll Surg 204(4):642-53||Profound Hypothermic Cardiopulmonary Bypass Facilitates Survival without a High Complication Rate in a Swine Model of Complex Vascular, Splenic, and Colon Injuries||2007|
|Velmahos, G. C., Spaniolas, K., Duggan, M., Alam, H. B., Tabbara, M., de Moya, M., Vosburgh, K.||J Trauma 63(2):285-8, discussion 288-90||Abdomainal Insufflation for Control of Bleeding After Severe Splenic Injury||2007|
|Stahl, J.E., Goldman, J.M., Rattner, D.W., Gazelle, G.S.||J. Surg Res.||Related Articles, Links Adapting to a New System of Surgical Technologies and Perioperative Processes Among Clinicians||2007 Jan. 31 (Epub ahead of print)|
|Ryou, M., Rattner, D., Pai, R., Thompson, C.||Surg Endosc. 12:677-80||Evaluating an Optimal Gastric Closure Method for Trans-Gastric Surgery||2007|
|Pai, R., Fong, D.G., Bundga, M.E., Odze, R.D., Rattner, D.W., Thompson, C.C.||Gastrointestinal Endoscopy 64:428-34||Transcolonic endoscopic cholesystectomy: a NOTES survival study in a porcine model.||2006|
|Rattner, D.W.||Surg Endosc 20:1802-8||Innovation, Disruption and the perils of success.||2006|
|Rattner, D.W., Kalloo, A.||Surg Endosc. 20:329-33||The ASGE/SAGES Working group on Natural Orifice Transluminal Endoscopic Surgery WHITE PAPER||2006|
|World First: Rectal Tumor Removed Through Anus, Avoiding Painful Abdominal Incisions||Medical News Today||Dec. 3, 2009|
|wbur.org||June. 22, 2009|
|A New Way to Perform Surgery||KTVU Channel 2||Jul. 15, 2008|
|Surgery Revolution||Philadelphia Bulletin||May 15, 2008|
|Open Wide. No, Wider. Are we ready for an era of 'natural-orifice surgery'?||Newsweek||Apr. 14, 2008|
|Scar-Free Surgery: In New Operation, Doctors Insert Tools Through Natural Orifices, Keeping Skin Intact||Boston Globe||Jan. 7, 2008|
|Novel NOTES Causes Docs to Rethink Incision Decision||Boston Business Journal||Jul. 13, 2007|
|Hype, Theories on NOTES Abound, But Where It Is All Headed Is Anyone’s Bet (PDF)||Gastroenterology & Endoscopy News||Jul. 2007|
|A New Step in Scarless Surgery||Proto||Summer 2007|
Video: CIMIT Life-Saving Innovation in Early Stage of Trauma.
VIDEO Q&A with David Rattner, MD:
» What is NOTES?
» NOTES vs. Endoscopy
» What is TEM?
» TEM Procedure and Collaboration
» What is the Boston-based NOTES Initiative?
» Is NOTES an Improvement over Traditional Laparoscopic Procedures
» What Procedures Might Benefit from the NOTES Approach?
» What is a Typical Minimally Invasive Thoracic Procedure?
» What is the Potential for NOTES?
» NOTES vs. Single-Port Surgery
» The Evolution of NOTES
» The Role of CIMIT
» When might Patients Benefit from NOTES?
Press Releases &
» July 2010: NOTES Progress Report